🩺 Nervigesic 150 mg Capsule (Pregabalin)
Generic Name: Pregabalin
Brand Name: Nervigesic 150
Manufacturer: Signature Phytochemical Industries
Formulation: Oral Capsule
Drug Class: Anticonvulsant
Prescription Status: Prescription-only
✅ Indications
Nervigesic 150 mg is indicated for the management of:
- Neuropathic Pain: Effective for conditions like diabetic neuropathy, post-herpetic neuralgia (nerve pain following shingles), and spinal cord injury-related pain.
- Fibromyalgia: Alleviates widespread musculoskeletal pain and tenderness.
- Partial-Onset Seizures: Used as an adjunctive therapy for adults with partial-onset seizures, with or without secondary generalization.
- Generalized Anxiety Disorder (GAD): Reduces anxiety symptoms in adults.
⚙️ Mechanism of Action
Pregabalin, the active ingredient, works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters, thus decreasing nerve excitability and providing relief from pain, anxiety, and seizures.
💊 Dosage & Administration
- Initial Dose: 75 mg twice daily or 50 mg three times daily, depending on the condition being treated.
- Maintenance Dose: May be adjusted by your healthcare provider based on response and tolerability, with a maximum dose of 600 mg per day.
- Administration: Swallow the capsule whole with a glass of water. Do not chew, crush, or split the capsule.
- Food: Can be taken with or without food.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it’s close to the time for your next dose. Do not double the dose to make up for a missed one.
⚠️ Warnings & Precautions
- Pregnancy & Breastfeeding: Consult a doctor before using during pregnancy or breastfeeding.
- Alcohol: Avoid alcohol consumption, as it may increase side effects like dizziness and drowsiness.
- Liver & Kidney Impairment: Use with caution in individuals with liver or kidney problems. Dose adjustments may be necessary.
- Elderly: Older adults may require adjusted dosing due to age-related kidney function decline.
- Allergic Reactions: Discontinue use and seek immediate medical attention if signs of severe allergic reactions occur (e.g., swelling, difficulty breathing).
❌ Common Side Effects
- Dizziness
- Drowsiness or fatigue
- Dry mouth
- Constipation
- Weight gain
- Edema (swelling)
- Blurred vision
Note: Most side effects are temporary. If they persist or worsen, consult your healthcare provider.
🔄 Drug Interactions
- CNS Depressants: Avoid taking Nervigesic with other central nervous system depressants (e.g., opioids, benzodiazepines), as this can increase the risk of sedation and respiratory depression.
- Thiazolidinediones: Used in diabetes management; may lead to weight gain and fluid retention when taken with pregabalin.
- GABA Antagonists: Concurrent use may reduce the effectiveness of pregabalin.
Always inform your healthcare provider of any other medications you are taking to avoid potential interactions.
💰 Price & Availability
- Price Range: ₹200–₹230 for a strip of 15 capsules.
- Availability: Available at pharmacies across India with a valid prescription.
📦 Storage Instructions
- Temperature: Store at room temperature (20°C to 25°C).
- Conditions: Keep in a cool, dry place, away from moisture, heat, and direct sunlight.
- Safety: Keep out of reach of children.
📝 Key Takeaway
Nervigesic 150 mg is an effective treatment for neuropathic pain, fibromyalgia, partial-onset seizures, and generalized anxiety disorder. It works by modulating neurotransmitter release, reducing pain, and controlling anxiety and seizures. Always follow your healthcare provider’s guidance for safe and effective use.
