Tadalis Sx 20

Tadalis SX

Tadalis SX – Tadalafil 20mg from the Fastest Delivery Provider. We ship Generic Cialis manufactured by Ajanta Pharma Ltd.

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Comprehensive Product Information Report

Tadalis SX (Tadalafil)

1. Product Overview

  • Brand Name: Tadalis SX
  • Generic Name: Tadalafil
  • Manufacturer: Ajanta Pharma Ltd.
  • Drug Class: Phosphodiesterase Type 5 (PDE5) Inhibitor
  • Formulation: Oral Tablets
  • Available Strengths: 10 mg, 20 mg
  • Primary Indication: Treatment of Erectile Dysfunction (ED) in adult males

2. Therapeutic Indication

Tadalis SX is indicated for the management of erectile dysfunction, a condition characterized by the inability to achieve or sustain an erection sufficient for satisfactory sexual performance. Tadalafil does not induce an erection without sexual stimulation.

3. Mechanism of Action

Tadalafil selectively inhibits the phosphodiesterase type 5 (PDE5) enzyme, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. By increasing cGMP levels, the drug facilitates smooth muscle relaxation and increased blood flow to the penis, enabling erection during sexual arousal.

4. Dosage and Administration

  • Standard Dose: 10 mg or 20 mg, taken as needed, approximately 30 to 60 minutes prior to sexual activity
  • Maximum Frequency: Once per day
  • Route: Oral
  • Administration: With or without food
  • Note: Not intended for continuous daily use in the as-needed form

5. Pharmacological Profile

Property Details
Absorption Rapidly absorbed; Tmax ≈ 2 hours
Bioavailability Not significantly affected by food
Half-life ~17.5 hours
Duration of Action Up to 36 hours
Metabolism Hepatic (CYP3A4 pathway)
Excretion Primarily fecal; minor urinary elimination

6. Safety and Side Effects

Common Adverse Reactions

  • Headache
  • Indigestion (dyspepsia)
  • Back pain
  • Muscle aches
  • Nasal congestion
  • Facial flushing

Less Common / Rare

  • Dizziness
  • Vision disturbances (e.g., color tinge, blurred vision)
  • Hearing impairment
  • Skin rash

Serious Adverse Events (Require Immediate Medical Attention)

  • Priapism (erection > 4 hours)
  • Sudden loss of vision or hearing
  • Chest pain, shortness of breath

7. Contraindications

  • Concurrent use of nitrates or nitric oxide donors
  • Known hypersensitivity to tadalafil or any excipients
  • Severe hepatic impairment
  • Recent history of myocardial infarction, stroke, or life-threatening arrhythmia
  • Uncontrolled hypotension or hypertension

8. Drug Interactions

Contraindicated Interactions

  • Nitrates (e.g., nitroglycerin): Risk of profound hypotension
  • Guanylate cyclase stimulators (e.g., riociguat)

Use with Caution

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): May increase tadalafil plasma levels
  • Alpha-blockers: Additive hypotensive effects
  • Antihypertensives: Monitor blood pressure closely
  • Alcohol: May potentiate hypotensive effects and increase dizziness

9. Precautions and Warnings

  • Not intended for use in women or individuals under 18 years of age
  • Use cautiously in patients with cardiovascular disease, renal/hepatic impairment, or anatomical penile deformities
  • Avoid combination with other ED therapies unless advised by a physician
  • Evaluate cardiovascular risk before initiating therapy

10. Storage and Handling

  • Storage Temperature: Below 30°C (86°F)
  • Conditions: Store in original packaging, protected from moisture and light
  • Shelf Life: Refer to packaging
  • Keep out of reach of children

11. Packaging and Presentation

  • Supplied in blister packs containing 4 or more tablets
  • Each pack clearly labeled with dose strength, batch number, expiry date, and manufacturer information

12. Regulatory and Legal Status

  • Legal Classification: Prescription-only (Rx)
  • Regulatory Status: Approved generic equivalent of Cialis® in multiple markets
  • Intellectual Property: Marketed post-expiry of original tadalafil patent

13. Market Position and Competitors

  • Key Competitors: Cialis, Vidalista, Tadarise, Sildalis, Kamagra
  • Market Niche: Cost-effective generic alternative for ED treatment with prolonged efficacy
  • Consumer Appeal: Known as the “weekend pill” due to its extended duration of action

14. Patient Counseling Information

  • Take only as prescribed by a healthcare provider
  • Sexual stimulation is required for the drug to be effective
  • Do not consume more than one tablet in 24 hours
  • Seek immediate care for painful or prolonged erections
  • Avoid excessive alcohol consumption before use

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