💊 Zoltrate 10mg Tablet
Generic Name: Zolpidem Tartrate
Brand Name: Zoltrate
Strength: 10 mg
Dosage Form: Oral Tablet
Drug Class: Non-benzodiazepine Hypnotic (Z-drug)
Manufacturer: Neuro Life Science
Prescription Status: Prescription-only
✅ Indications
Zoltrate 10mg is prescribed for the short-term treatment of insomnia, particularly for individuals who experience difficulty falling asleep or maintaining sleep. It is designed to improve sleep onset and reduce nighttime awakenings, helping patients achieve a more restful and uninterrupted sleep cycle.
⚙️ Mechanism of Action
Zolpidem, the active ingredient in Zoltrate, works by interacting with the GABA-A receptors in the brain. This enhances the effects of GABA, an inhibitory neurotransmitter, leading to CNS depression that results in sedation, sleep initiation, and maintenance.
💊 Dosage & Administration
- Initial Dose: 10 mg taken orally, just before bedtime.
- Timing: Take on an empty stomach for optimal absorption, approximately 30–45 minutes before sleep.
- Duration: Recommended for short-term use (2–4 weeks).
- Caution: Ensure at least 7–8 hours of sleep following administration to avoid next-day impairment.
- Elderly or Hepatically Impaired: Lower starting doses (5 mg) may be considered to reduce the risk of side effects.
⚠️ Warnings & Precautions
- Risk of Dependence: Prolonged use can lead to tolerance, dependence, or withdrawal symptoms.
- CNS Depression: May impair coordination and alertness; avoid operating machinery or driving.
- Alcohol Interaction: Alcohol may enhance the sedative effects of Zoltrate, increasing the risk of serious side effects.
- Pregnancy & Lactation: Not recommended unless absolutely necessary.
- Liver Impairment: Use with caution and adjust the dose if necessary.
- Elderly Patients: More sensitive to the sedative effects; monitor closely for adverse effects.
❌ Side Effects
Common:
- Drowsiness
- Dizziness
- Headache
- Nausea
- Memory issues or amnesia
Serious (seek immediate medical help if):
- Unusual changes in behavior or mood
- Sleepwalking or engaging in activities while not fully awake
- Severe allergic reactions (rash, swelling, difficulty breathing)
🔄 Drug Interactions
- Other CNS Depressants (e.g., alcohol, opioids): Can increase sedative effects and lead to dangerous CNS depression.
- Antidepressants and Antipsychotics: May alter zolpidem’s effectiveness or enhance side effects.
- Antifungals, Antibiotics, and Anticonvulsants: May affect zolpidem metabolism; dosage adjustments may be needed.
📦 Storage Instructions
- Store at room temperature (15°C to 30°C).
- Keep in a dry place, away from light and moisture.
- Keep out of reach of children and pets.
📝 Summary
Zoltrate 10mg is an effective short-term treatment for insomnia, providing rapid sleep onset and improved sleep quality. It is important to use this medication under medical supervision due to the risk of dependency and potential side effects, particularly when used beyond the recommended duration.